1049-117 B-type natriuretic peptide is a biochemical predictor of myocardial contractile reserve during dobutamine stress echocardiogram

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Clinical and Biochemical Assessments of Circulating B-Type Natriuretic Peptide as a Useful Marker in Pediatric Cardiac Patients

Background Although the left ventricle is the major site of BNP secretion in response to cardiac pressure or volume overload, the myocytes of both atria and ventricles secrete B- type natriuretic peptide (BNP). This study aimed to assess and compare the plasma levels of BNP in common pediatric cardiac diseases to clarify its pathophysiological role and evaluate its po...

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[Predictors of myocardial contractile reserve in patients with nonischemic dilated cardiomyopathy. An echo-stress dobutamine study].

INTRODUCTION AND OBJECTIVES Myocardial contractile reserve studies with low-dose dobutamine echocardiography have been shown to be useful to assess functional myocardial status. However, the variables associated with contractile reserve after inotropic stimulation are not well known. PATIENTS AND METHOD We studied 50 patients (35 men, mean age 56.4 +/- 9.5 years) with nonischemic dilated card...

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B Type natriuretic peptide: a good omen in myocardial ischaemia?

The natriuretic peptide family consists of a number of structurally homologous but genetically distinct polypeptide mediators. The peptides are highly conserved across mammalian and invertebrate species and, in humans, are released from various tissues in response to physiological and pathological stimuli. All the peptides have at their core a 17-amino acid disulfide ring essential for receptor...

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Reduced contractile reserve of the systemic right ventricle under Dobutamine stress is associated with increased brain natriuretic peptide levels in patients with complete transposition after atrial repair.

AIMS To compare B-type natriuretic peptide (BNP) levels with response of systemic right ventricular function to Dobutamine stress. METHODS AND RESULTS Sixteen patients aged 25.6 +/- 3.7 years (eight each after Senning or Mustard repair of complete transposition) were studied. Transoesophageal imaging was performed in the catheterization laboratory under general anaesthesia before and at the e...

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Washout Reflects Impaired Myocardial Contractile and Relaxation Reserve During Dobutamine Stress Due to Mitochondrial Dysfunction in Dilated Cardiomyopathy Patients

Methods Twenty DCM patients (New York Heart Association functional class I–III) underwent myocardial Tc-MIBI scintigraphy and cardiac catheterization. Myocardial MIBI uptake was quantified as an early and delayed heart-tomediastinum ratio, and WR was calculated. Maximum first derivative of left ventricular (LV) pressure (LV dP/dtmax) (an index of myocardial contractility) and LV pressure half-t...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2004

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(04)90734-6